Day 2

All times shown in CEST

Recordings are passcode-protected (registrants only)

9:00 - 10:00

Session 5: Short-term scientific missions

Results from ERNEST funded short-term scientific missions

Chairs: Marcel Bermúdez & Friederike Wunsch


Leire Borrega (University of the Basque Country, Spain)

Alessandro Nicoli (Leibniz-Institute for Food Systems Biology at the Technical University of Munich, Germany)

David Reiner-Link (University of Copenhagen, Denmark)


15 min Break

Join us for Networking!

10:45 - 12:00

Chairs: Miriam Scarpa & Theresa Noonan


Hans Bräuner-Osborne (University of Copenhagen, Denmark)

Detailed signaling map of the orphan GPR139 receptor

Alena Randáková (Czech Academy of Sciences, Prague, Czech Republic)

Biased agonists of muscarinic receptors

Sabina Podlewska (Maj Institute of Pharmacology Polish Academy of Sciences, Kraków, Poland)

Signaling bias of the selected mu-opioid receptor agonists – behavioral and molecular modeling studies

Abdul-Akim Guseinov (Queen's University Belfast, Northern Ireland) (not recorded upon request)

Neurotensin receptor 1 allosteric sites explored by probe molecular dynamics simulations and BRET-based assays

Flash Poster Talks 2

Pre-recorded 3 minute talks selected from submitted abstracts

Chairs: Miriam Scarpa & Eloise Euston


2.1 Chloe Hicks (Duke University, USA)

Location Bias Contributes to Functionally Selective Responses of Biased CXCR3 Agonists to Regulate Inflammation

2.2 Bethany Strellis (Institute of Molecular, Cell and Systems Biology, University of Glasgow, UK)

Mutation of mGluR5 intracellular serine residues results in biased signalling towards G protein coupling

2.3 Kyler Crawford (Medical College of Wisconsin, USA)

Dimeric form of CXCL12/SDF-1 binds to atypical chemokine receptor-1 (DARC/ACKR1)

2.4 Owen Underwood (School of Life Sciences, University of Nottingham & COMPARE, UK)

Use of intramolecular biosensors to monitor mu-opioid receptor-induced conformational changes of β-arrestins

2.5 Marco Bonfanti (University of Strathclyde, Glasgow, UK)

Exploring the structural basis of Protease activated receptor 4 (PAR4) protein interactions by proteomic analysis

2.6 Yasmin Aydin (Leipzig University, Germany)

Mapping Flexible Interactions of β-Arrestin with a Secretin-Like GPCR via Genetically Encoded Crosslinkers

2.7 Nil Casajuana Martin (Universitat Autonoma de Barcelona, ES)

The Gi and Gs protein-coupled µ-opioid-galanin Gal1 receptor heterotetramer

2.8 Gloria Somalo Barranco (Université de Paris, France & IQAC-CSIC, Barcelona, Spain)

Mitochondrial-targeted caged melatonin supports the presence of melatonin MT1 receptors in mitochondria inhibiting mitochondrial respiration

2.9 Uche Agwuegbo (King’s College London, UK)

Differentially glycosylated FSHR ligands as potential modulators of FSHR quaternary complexes and FSHR-dependent signalling

12:40 - 13:30

Poster presentations

Opportunity to network and visit poster presenters in Wonder

13:30 - 14:00

Lunch

15 min Break

Join us for Networking!

17:30 - open end

Networking